Eutirox for weight loss: dosage and reviews

Pharmacodynamics and pharmacokinetics

Eutirox is a drug created on the basis of a synthetic levorotatory isomer of thyroxine . Its use affects the growth and development of tissues and metabolic processes.

Small dosages can have an anabolic effect on fat and protein metabolism. Medium doses stimulate growth and development, metabolic processes, normalize the need for oxygen in tissues, as well as the functioning of the heart, blood vessels and nervous system. The development of the therapeutic effect appears after 7-12 days, remaining stable during this time and after treatment is discontinued.

Absorption of levothyroxine sodium occurs in the small intestine, directly in its upper section. Eating food affects the absorption of the active substance, significantly reducing it. The maximum concentration of the component is achieved 5-6 hours after application.

The main part of the drug binds to serum proteins. Thyroid hormones are then metabolized, primarily in the kidneys, liver, brain and muscle tissue. Excretion of metabolites occurs through the kidneys and intestines.

What is Euthyrox

The synthetic drug is an analogue of thyroxine, a thyroid hormone. Thanks to levothyroxine sodium, the active ingredient of Euthyrox, the drug has a beneficial effect on tissue development, growth and metabolism. Eutirox is a drug for replenishing thyroid hormone deficiency. A small dosage of the drug increases the rate of synthesis of proteins and fats, while a medium dose is aimed at the development and growth of tissues and their need for oxygen. The use of a large amount of the drug inhibits the functioning of the hypothalamus and pituitary gland (endocrine glands).

Contraindications for use

Taking the drug is contraindicated if:

• high sensitivity to its constituent substances;
• untreated thyrotoxicosis, pituitary and adrenal insufficiency;
• pregnancy in combination with antithyroid drugs.

It is not recommended to use Eutirox for the treatment of patients with acute forms of myocardial infarction, myocarditis and pancarditis . The lactose content in the drug makes it prohibited for use by patients with rare hereditary diseases associated with galactose intolerance, lactase deficiency or glucose-galactose malabsorption syndrome.

Caution in use requires such diseases as: coronary heart disease, arterial hypertension, diabetes mellitus, arrhythmia .

Instructions for Eutirox (Method and dosage)

As the instructions for use of Eutirox indicate, this medicine is taken orally. In this case, the daily dose is set individually, taking into account the indications and characteristics of the patient.

It is recommended to take the daily dosage in the morning, on an empty stomach. The tablet must be swallowed whole with liquid. When replacement therapy for hypothyroidism is carried out, the dose is determined depending on the weight of the patients. When treating children under 3 years of age, the medicine is given half an hour before the first feeding. The tablet must be dissolved in water until a thin suspension is formed.

Severe and long-term form of hypothyroidism requires initiation of treatment with caution and in small dosages. Then the dose is gradually increased to 25 mcg or more. In such cases, the drug is usually taken constantly, but strictly as prescribed by the attending physician.

Contraindications

Before the therapeutic course, it is important to learn more about Eutirox - the instructions for use for weight loss will tell you about all the contraindications. Eutirox is not prescribed to pregnant women for weight loss, but is used as a medicine to replenish hormone deficiency in the thyroid gland. When taking the drug during pregnancy, you should be aware that it affects the fetus. Lack of thyroxine and its excess can affect the baby’s health and lead to serious complications, such as mental retardation.

Overdose

In case of an overdose of Eutirox, a significant increase in the rate of metabolic processes is possible. This leads to the development of hyperthyroidism , and especially when the individual threshold of tolerance to levothyroxine sodium , as well as a too rapid increase in the therapeutic dose.

In this case, such symptoms of overdose develop as: arrhythmia, tachycardia , heartbeat irregularities, angina pectoris , muscle and headaches, tremor, hyperemia, fever , vomiting, benign intracranial hypertension , anxiety, insomnia , hyperhidrosis , weight loss and so on.

Treatment depends on the symptoms that appear. It is possible that the doctor will reduce the daily dose or recommend taking a break or prescribing beta-blockers . As a result of taking excessively high doses, plasmapheresis . When the symptoms of overdose have resolved, treatment is resumed with caution, using small doses.

special instructions

Before starting replacement therapy with thyroid hormones and performing a thyroid suppression test, diseases or abnormalities such as acute coronary insufficiency, angina pectoris, atherosclerosis, arterial hypertension , pituitary insufficiency or adrenal insufficiency should be excluded or treated. This also applies to the functional autonomy of the thyroid gland.

It is recommended to exclude the development of hyperthyroidism during treatment in patients suffering from coronary and heart failure, tachyarrhythmias . For this reason, it is necessary to regularly monitor the concentration of thyroid hormones.

If there is a suspicion of the occurrence of functional autonomy of the thyroid gland, then before treatment it is necessary to perform reactions to the administration of thyroid hormone-releasing hormone, known as the TRH test, as well as suppressive scintigraphy.

Postmenopausal women with diagnosed hypothyroidism and an increased risk of osteoporosis should not have high physiological concentrations of the active component in the serum. In this case, it is necessary to regularly monitor the functioning of the thyroid gland.

The use of levothyroxine sodium in metabolic disorders accompanied by hyperthyroidism. Exceptions include concomitant use of antithyroid drugs in the treatment of hyperthyroidism. In case of switching to treatment with another drug, dose adjustment is required taking into account the therapeutic effect and laboratory data.

Interaction

Concomitant use of this drug with tricyclic antidepressants may enhance their effect.

Levothyroxine sodium reduces the effectiveness of cardiac glycosides.

Combination with cholestyramine, colestipol, aluminum hydroxide reduces the concentration of the active substance in plasma due to inhibited absorption in the gastrointestinal tract. Therefore, between doses of these drugs you need to maintain an interval of 4-5 hours.

The simultaneous use of Eutirox and anabolic steroids, asparaginase, tamoxifen can lead to pharmacokinetic interaction at the level of binding to plasma proteins. It has also been found that protease inhibitors, namely ritonavir + lopinavir and indinavir , can affect the effectiveness of this drug. It is necessary to monitor the concentration of thyroid hormones and make timely dosage adjustments.

Combination therapy with phenytoin often increases the concentration of levothyroxine sodium, accelerating its metabolism. This drug may reduce the effectiveness of hypoglycemic agents and enhance the effect of anticoagulants.

Use with sevelamer reduces the absorption of the active substance, and tyrosine kinase inhibitors, aluminum-containing, iron-containing drugs and calcium carbonate reduce its effectiveness. When consuming products containing soy, a decrease in the absorption of the active component in the gastrointestinal tract was noted.

Analogs

Level 4 ATC code matches:
Thyroidin

Levothyroxine

Thyrotome

Tyreocomb

L-Thyroxine

The main analogues of the drug are represented by L-thyroxine and Levothyroxine sodium . Also have a similar effect: Thyroidin and Triiodothyronine hydrochloride.

Compound

One tablet of a hormonal drug contains the active substance in the amount indicated on the product packaging. Levothyroxine sodium is the sodium salt of L-thyroxine and, after metabolism in the kidneys and liver, affects tissue development. Among the additional substances, in addition to lactose monohydrate, there are: croscarmellose sodium, magnesium stearate, gelatin, corn starch. Before using the medication, be sure to read the composition of the product in the instructions to avoid allergic reactions and the development of side effects.

Eutirox and weight

Many women suffering from thyroid disorders are concerned about the question: can weight gain occur during treatment with Eutirox. But reviews show that the use of hormonal drugs has different effects on both the weight of patients and their general condition. Therefore, in some women it increases, while in others it decreases.

For this reason, some believe that Eutirox can be used for weight loss, especially since at one time a number of hormonal drugs were actually used to adjust body weight, for example, in athletes. However, experts say that Eutirox for weight loss should not be taken without specific indications for this. Sometimes reviews for weight loss report successful cases, but usually this method of eliminating excess weight leads to serious deviations in the functioning of the body.

Reviews about Eutirox

As reviews of Eutirox show, this drug is often used in clinical practice, since thyroid disorders worry many patients.

Basically, reviews of Eutirox 50 mcg report that this particular dosage is used in the treatment of most diseases. However, it is important to start therapy with small doses, for example, 12.5 mcg, then increase to 25 mcg and so on. The main thing is to do it gradually.

A large number of questions arise from patients who have recently been prescribed the drug. Therefore, they are interested in how to take tablets and Eutirox - is it a hormonal drug or not? Women are also concerned about whether various side effects actually develop during treatment and whether it can be used for weight loss?

Often, patients who take this medication report that it is well tolerated and has minimal side effects. Of course, important conditions are: strict adherence to dosage, timely testing and lifestyle changes.

Unfortunately, you can find messages in which patients report that they continue to experience severe pain, drowsiness, and depression. It has also been noted that some people experience weight loss or gain. In any case, all questions should be discussed with your doctor, which will allow you to replace the treatment or adjust the dosage.

Price

In any pharmacy in Russia, including the capital, you can buy the hormonal medicine Eutirox only with a doctor’s prescription or order it inexpensively from a catalog. Before you buy from an online store, you need to consult a specialist. The doctor will tell you how to calculate the dose of Eutirox by weight. The price of the medicine depends on the place of sale, manufacturer and dosage. The cost of the drug is 100-300 rubles per package of 100 tablets. Below is the approximate cost of production for 100 tablets (Moscow):

Eutirox price, where to buy

The price of Eutirox 50 mcg for 50 pieces in Moscow pharmacies is 130-150 rubles.

You can buy Eutirox 50 mcg in online pharmacies for 106-130 rubles.

The price of Eutirox 100 mcg varies between 117-150 rubles, and Eutirox 25 mcg can be purchased for 86-100 rubles.

• Online pharmacies in RussiaRussia
• Online pharmacies in UkraineUkraine
• Online pharmacies in KazakhstanKazakhstan

ZdravCity

• Eutirox tablets 125 mcg 100 pcs. Merck KGaA
  154 rub. order
• Eutirox tablets 88mcg 100 pcs.Merck KGaA

  124 RUR order

• Eutirox tablets 25 mcg 100 pcs. Merck KGaA

  93 RUR order

• Eutirox tablets 150mcg 100 pcs. Merck KGaA

  RUB 156 order

• Eutirox tablets 112mcg 100 pcs.Merck KGaA

  148 RUR order

Pharmacy Dialogue

• Eutirox (tab. 137 µg No. 100) Merck KgaA

  148 RUR order

• Eutirox (tab. 88 µg No. 100) Merck KgaA

  119 RUR order

• Eutirox (tab. 125 µg No. 100) Merck KgaA

  148 RUR order

• Eutirox (table 150 µg No. 100) Merck KgaA

  148 RUR order

• Euthyrox (table 50 µg No. 100) Merck KgaA

  107 RUR order

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Pharmacy24

• Eutirox 25 mcg No. 100 tablets Merck KGaA, Nimechchina
  107 UAH. order
• Eutirox 50 mcg No. 100 tablets Merck KGaA, Nimechchina

  121 UAH order

PaniPharmacy

• Eutirox tablets Eutirox tablets 150 µg No. 100 Germany, Merck KGaA

  180 UAH order

• Eutirox tablets Eutirox tablets 25 µg No. 100 Germany, Merck KGaA

  111 UAH order

• Eutirox tablets Eutirox tablets 50 µg No. 100 Germany, Merck KGaA

  128 UAH order

• Eutirox tablets Eutirox tablets 125 µg No. 100 Germany, Merck KGaA

  175 UAH order

• Eutirox tablets Eutirox tablets 100 µg No. 100 Germany, Merck KGaA

  149 UAH order

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Instructions for using Eutirox for weight loss

Some people use the medication to speed up the process of losing extra pounds. Judging by the positive reviews, it is possible to lose weight with Eutirox - the drug improves metabolism, i.e., slow metabolism is normalized, which has a positive effect on the elimination of fat deposits. The first to use Eutirox for weight loss were athletes, bodybuilders and bodybuilders. Weight loss occurs due to the special properties provided by the medication:

• reduces appetite;
• accelerates metabolism associated with burning calories;
• promotes glucose absorption;
• stimulates the nervous system, which brings the body into an active state and the person wants to move.

The course of using Eutirox for weight loss is 28 days. Take the tablets with plenty of water. To achieve results, you should make proper nutritional adjustments when taking the drug and include foods containing large amounts of protein and fiber in your daily diet. A high dose of the drug of 150-200 mcg helps to lose weight, but it is recommended to take it in an average amount. How to take Eutirox? Recommendations must be followed:

1. Reception begins with 50 mcg per day, gradually increasing to 300 mcg.
2. The daily dose of Eutirox is divided into 3 doses.
3. You can take Eutirox tablets no later than 6 pm.
4. The medicine should be taken before meals or 2 hours after.

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