Reduxin - contraindications and side effects, cheaper analogues and prices

The best analogues.

Excess weight is a global problem of our time. Physical activity (stretching, strength training) and diets do not always produce results for various reasons. And here drug therapy comes into play. When choosing medications, preference is often given to Reduxin. In case of obesity, it can give good results.

The medicine is classified as expensive. Therefore, the issue of replacement remains relevant. And what analogues of Reduxin are most effective in the fight against extra pounds? We suggest you familiarize yourself with several popular options.

Reduxin - description and indications

The drug Reduxin belongs to the group of weight loss drugs with a central mechanism of action. Available in tablet form, produced in Russia. The composition includes 15 mg of sibutramine, 153.5 mg of microcrystalline cellulose. The cost of 30 capsules is 1,700 rubles.

The drug Reduxin Met differs from Reduxin in composition and group.

In Reduxin Met, which belongs to the hypoglycemic biguanide drugs, in addition to sibutramine and cellulose, metformin is added. This is a unique medicine, the packaging of which contains tablets and capsules with different components (metformin is separated into a separate form). A box of this drug 30+60 tablets costs 2800 rubles.

Another product from the group of dietary supplements is also produced under the Reduxin brand - Reduxin Light Strengthened Formula, intended for those losing weight. The difference between the products is cardinal, because Reduxin Light has the following composition:

linoleic acid;
yam root;
yam extract.

The pharmacological action of Reduxin is due to the presence of sibutramine. This substance increases the content of special elements in the body, due to which the activity of serotonin and adrenergic receptors increases. This causes a decrease in appetite and a feeling of fullness. The substance also affects adipose tissue, provokes a decrease in cholesterol, triglycerides, and uric acid.

For stagnation of bile and other problems with the gallbladder, it is recommended to take choleretic drugs. One of the most popular prescriptions for gastroenterologists is taking Hofitol tablets. Read more in the article: “chophytol: indications for use and contraindications.”

Metformin in Reduxin Met reduces hyperglycemia without stimulating insulin production. The substance also helps normalize fat metabolism and reduce cholesterol in the blood. Indications for taking the drugs are the same:

nutritional obesity (BMI over 27);
obesity with diabetes mellitus;
dyslipidemia.

The drug Reduxin Light has the same indications, and also serves as an additional source of linoleic acid.

Chemical composition

The main active component of reduxin is sibutramine in the form of hydrochloride (hydrochloric acid salt) monohydrate.

The drug is a prodrug in its action . This means that the effect on the body is not sibutramine itself, but its derivatives formed as a result of metabolism in the body. In this case, these are compounds belonging to the class of primary and secondary amines.

Sibutramine appears as a white or yellowish crystalline powder with a bitter taste. The substance dissolves well in water.

Reduxin also contains microcrystalline cellulose (enterosorbent), which promotes:

uniform release of sibutramine from the capsule;
removal of toxins and toxic metabolic products from the body.

Reduxin is on sale in the form of blue and blue capsules. They differ from each other in the amount of the main active ingredient.

Blue capsule No. 2 contains:

sibutramine hydrochloride monohydrate - 10 mg;
microcrystalline cellulose - 158 mg.

Blue capsule No. 2 contains 15 mg of sibutramine and 153 mg of enterosorbent.

The capsule shell is made of calcium salt of stearic acid (emulsifier E 572) and food coloring.

The drug can be purchased at a pharmacy only with a prescription from an endocrinologist.

Sibutramine is on the List of Potent Drugs, which was approved on December 29, 2007, but not in combination with microcellulose. Therefore, Reduxin can be purchased using prescription form No. 107.

Contraindications, negative effects

Before starting treatment, it is better to clarify in advance the contraindications and side effects of Reduxin. Do not take the drug if you are allergic or intolerant to any of the components. There will be no effect from taking it, and harm is also possible for serious causes of obesity:

hormonal dysfunctions;
hypothyroidism, etc.

The list of contraindications includes anorexia, bulimia - with such disorders, the medicine can only do harm, causing even greater appetite disturbances. Other prohibitions on treatment include:

generalized nervous tics;
psychopathy;
taking antidepressants, antipsychotics, MAO inhibitors, tryptophan, anti-obesity medications.

The drug can be harmful in case of heart pathologies - coronary artery disease, insufficiency of function, arrhythmias. You should not drink it if you have had a stroke.

Lisoprim ENT is prescribed for resorption for various diseases of the pharynx and throat. This remedy is indicated to relieve inflammation and accelerate the healing of the mucous membrane. Read more in the article: “lisoprim ENT indications for use.”

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Goldline is used in the treatment of obesity as a means of regulating appetite. Read more >>

Side effects usually develop at the very beginning of therapy, in the first month, and then disappear or weaken. Most often these include dry mouth, headaches and dizziness. Many people experience changes in taste and experience paresthesia. The heart often reacts with tachycardia, increased blood pressure, and increased heart rate. Nausea, constipation, itchy skin, and changes in blood composition may also appear.

The best analogues

You can replace Reduxin with the following analogues of drugs, many of which are sold in pharmacies without a doctor’s prescription:

Goldline. An inexpensive analogue of the original product from a Russian manufacturer. Has the same active composition. It is most effective when combined with proper nutrition and exercise, ensuring stable fat burning. It has several contraindications: pregnancy, prostatitis, nervous system disorders and glaucoma. Prescribed exclusively to adults without individual intolerance.
Lindax. A popular Czech product. Not found in retail sales very often. Presented in two dosages of 10 and 15 mg.
Slimia. Often prescribed by doctors to treat obesity. The drug is produced in India. Sold in pharmacies in a dosage of 15 mg. It is prescribed to patients who, for various reasons, cannot lose weight using non-drug methods.
Meridia. Another fairly effective analogue of the drug, intended for patients with excess body weight. Available dosages are 10 and 15 mg.

In addition to the listed drugs, all kinds of dietary supplements are also available in pharmacies. Manufacturers in advertising talk about their miraculous properties. But in reality they have no effect. It is easy to understand that the product will not help in any way - it does not contain sibutramine.

These drugs do not have an extensive list of contraindications and side effects. However, they are absolutely useless in the fight against obesity. If you are faced with this problem, we recommend that you do not do anything on your own, but go to a doctor who will conduct a comprehensive examination and prescribe the appropriate medication.

Instructions for use

It is enough to drink Reduxin once a day, but the dose is set individually. To clarify tolerance, you should first drink the minimum dosage and gradually increase it. Treatment with Reduxin is carried out in the morning; without chewing, drink the tablet with a full glass of water.

At the same time, you can eat or take the product on an empty stomach - the effectiveness will not change.

The initial dose is 10 mg; if side effects immediately occur, the dose is reduced to 5 mg.

During Reduxin therapy, body weight regression should be at least 5% within a month. Otherwise, add a dose of up to 15 mg or more. The course lasts 3 months, after which you can take a break. You can continue taking it only if you have a stable positive response to therapy. The maximum duration of taking Reduxin is 2 years.

Reduxin Met is taken in this way:

drink 850 mg of metformin and 10 mg of sibutramine (capsule and tablet) at the same time;
take in the morning with plenty of water;
combine treatment with food consumption (breakfast).

After 2-3 weeks, you can increase the dosage of metformin to 2 tablets, the maximum dose is 2550 mg/day. The total duration of therapy is 1 year, no more. Reduxin Light is taken 2 capsules/day for weight control, 6 capsules for serious weight loss. Treatment is carried out during meals, the course is 2 months.

Effect on the body

The prodrug has an anorexic effect on the body, stimulating the center in the brain responsible for satiety.

The drug is used only in the treatment of obesity caused by overeating, as well as complicated by diabetes mellitus and slow metabolism.

Mechanism of action

Several interconnected centers in the brain are responsible for the feeling of hunger in a person.
When they are excited, biologically active substances called neurotransmitters are released. This leads to a decrease in the concentration of the hormones serotonin and norepinephrine in the body. The first is responsible for a feeling of comfort and general well-being, and the second is responsible for a surge of vitality and energy. A lack of serotonin and norepinephrine leads to a feeling of weakness, psychological discomfort and false hunger. For this reason, a person can eat food not only to maintain physiological health, but also for the purpose of:

stress relief;
relaxation;
getting pleasure.

Reduxin, absorbed into the gastrointestinal tract by almost 80%, breaks down into primary and secondary amines, which block the reuptake of serotonin and norepinephrine, maintaining their constant concentration in the body.

As a result of this process, the feeling of hunger does not occur, and the need for food for pleasure is reduced. After taking the drug Reduxin, a person begins to eat only at the moment of physiological need for food.

After taking the prodrug in the body:

the concentration in the blood of high-density lipoproteins, which are classified as “good” cholesterol, increases;
the level of triglycerides, total cholesterol, and low-density lipoproteins decreases;
Thermogenesis is activated, leading to the breakdown of brown fat into thermal energy and water.

IMPORTANT! Sibutramine is not addictive. It does not have the opposite effect.

Reception scheme

The drug is taken one capsule per day.
It is advisable to do this in the first half of the day, washing down with water in an amount of at least 200 ml, which is necessary for the swelling of crystalline microcellulose in the stomach. Treatment begins with blue capsules. Weight loss is considered normal - from one to one and a half kg per week. If weight loss is slow, then the doctor prescribes blue capsules.

The course should not last longer than three months. Then they take a break of four to six weeks to restore the body and consolidate the results obtained.

Reduxin is not recommended for use for longer than two years, even in periodic courses.

The drug has an extensive list of contraindications for use and side effects. For this reason, it should be used only as prescribed by an endocrinologist and under his supervision.

The price of the drug Reduxin produced by OZON starts from 1800 rubles. for 30 pcs. 10 mg each.

Analogues of the drug

There are a number of analogues of the drug without a prescription, and only some of them are cheaper. Products based on sibutramine are quite expensive due to the difficulties of production. There are also a number of drugs with similar effects that differ in composition. Here is a list of popular remedies:

Medicine	Compound	Price, rubles
Goldline	Sibutramine, cellulose	2030
Orsoten	Orlistat	740
Listata	Orlistat	640
Xenical	Orlistat	850
Lindaxa	Sibutramine	1100

You can replace Reduxin with a drug with a different active substance only after the new course has been approved by your attending physician.

Goldline plus

Goldline is not a cheaper drug, but it is prescribed no less often, since Reduxin is often not available in pharmacies. It is a complete structural analogue of Reduxin, contains sibutramine (15 mg), cellulose (153.5 mg). .

A combined remedy, Goldline helps to achieve faster satiety and reduce the need for food.

Cellulose enhances the effect of treatment. It serves as a sorbent, binding toxins and breakdown products, and is considered a good detoxification component. It is cellulose that helps remove metabolites that are responsible for the development of endogenous toxicosis.

It is recommended to drink this remedy if all other weight loss medications are ineffective. Additionally, a reasonable diet and physical activity must be used. The course of therapy is 1-2 years.

Slimia

This is another product based on sibutramine (10-15 mg) and cellulose (95.5 mg). As you can see, there is a reduced amount of sorbent here compared to Reduxin. The drug is available in the form of gelatin capsules. Its price is 1400 rubles. Like its analogues, Slimia is widely recommended for the treatment of obesity not caused by organic causes. As an element of complex therapy, Slimia is indicated for the following conditions:

atherosclerosis;
dyslipidemic syndrome;
increased uric acid;
dyslipoproteinemia.

It is prohibited to be treated with Slimia for anorexia, bulimia, mental disorders, systemic tics, taking medications that act on the central nervous system, or for serious heart pathologies. Additionally, the manufacturer lists prostate adenoma, glaucoma, and adrenal tumors as contraindications. Dose per day - 5-15 mg. In case of overdose, respiratory and cardiac problems may occur.

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Xenical

This medicine is also used as a remedy for obesity, but has a different active substance and works in a different way. It contains orlistat, an inhibitor of lipases in the gastrointestinal tract. The price of the medicine is 850 rubles/21 capsules. Xenical works for a long time, localizing in the stomach and small intestine. It prevents specific enzymes from breaking down fats into fatty acids and monoglycerides. Undigested fats cannot be absorbed, as a result, food loses calorie content and body weight decreases.

Weight loss is observed after 2 weeks from the start of treatment. Side effects usually occur at the beginning of therapy and affect the gastrointestinal tract - diarrhea develops, oily discharge from the rectum, gases, and a frequent urge to defecate. Possible abdominal pain. Later such phenomena disappear. Indications of the drug:

obesity;
diabetes;
atherosclerosis.

Xenical is contraindicated in case of cholestasis, malabsorption syndrome. It should also not be taken by pregnant women or during lactation.

Cheap analogues of Reduxin

In addition to structural ones, Reduxin has substitutes for the effect on the body, among which you can choose inexpensive and effective means.

Turboslim

Turboslim is produced in capsules with active ingredients of plant origin - papaya and guarana extracts, bioflavonoids of citrus plants, algae extracts, as well as vitamins B1, B2, B3, vitamin C and E. The medication is produced in night and day capsules, as well as in tea and coffee .

Turboslim is a biologically active supplement (BAA) that helps reduce body weight.

Turboslim daily capsules enhance metabolism and improve microcirculation of fluid in the cells of the body's tissues. The drug has a positive effect on the immune system, normalizes lipid balance, breaks down excess fat molecules in the subcutaneous tissue, and improves the condition of the skin.

Turboslim night capsules burn fat deposits during sleep and promote good and sound sleep. Taking night capsules helps normalize processes in the intestines and facilitate easy bowel movements in the morning. Tea and coffee reduce appetite and remove excess fluid from the body.

Turboslim should not be used if:

allergies to plant composition;
cardiological and systemic pathologies – arrhythmias, coronary artery disease, hypertension;
systemic atherosclerosis;
insomnia;
lactation and pregnancy, as well as in pediatrics.

Tea Turboslim

During the day you need to take capsules for breakfast and during lunch, and also take 1 capsule during dinner. The course of taking capsules is 1 month. One month after the end of the course of therapy, you can repeat the course.

Turboslim coffee and tea are recommended to be taken in the first half of the day. Drink coffee once a day, tea can be drunk twice.

Adverse reactions do not occur frequently with dietary supplements and can be expressed by the following symptoms:

skin rashes, itching and hyperemia;
overexcitability of the nervous system;
irritability;
dizziness and insomnia;
tachycardia and pressure fluctuations;
dyspepsia with defecation disorders.

Xenical

Xenical is a medication for weight loss, the effect of which has been proven in clinical studies. The active ingredient in Xenical is orlistat. The medication is produced in gelatin capsules with active powder inside. Xenical resists the absorption of 30% of fats that enter the body endogenously (with food). Due to the fact that a large amount of fat does not enter the body, its own fat accumulations are consumed. The active ingredient begins to actively remove fat from feces within a day or two.

Prescribe medication for:

obesity 2-4 degrees;
diabetes mellitus and increased body weight.

Do not use Xenical in therapy for:

malabsorption;
cholestasis;
allergies to the medicinal composition.

Mechanism of action

Also not used in pediatrics under 12 years of age, during pregnancy and breastfeeding.

The standard single dosage of the drug is 120 mg (1 capsule) three times a day. Capsules should be taken with meals or no later than 60 minutes after meals. If the foods you eat do not contain fat at all, then you can skip taking the medicine.

You should not take more than 3 capsules per day, because this will not lead to increased fat burning and the weight loss process will not become faster. After completing the course of therapy with Xenical, fat will leave the body with feces for another 2-3 days.

You cannot use Xenical with fat-soluble vitamins A, E, K and D, because the medication inhibits the absorption of vitamins in the intestines.

Side effects:

disturbances of intestinal motility;
flatulence, diarrhea or constipation;
epigastric or abdominal pain;
frequent urge to have bowel movements;
rectal bleeding;
decreased blood sugar;
allergic skin rashes.

Orsoten

Orsoten capsules are made on the basis of orlistat, which is an inhibitor of lipases in parts of the digestive system. Orsoten has a prolonged action. The mechanism of action is aimed at suppressing lipases in the small intestine and stomach.

In these organs, orlistat forms a covalent bond with enzymes, which blocks the enzyme's ability to break down triglycerides, free cholesterol molecules and monoglycerides and prevents their absorption into the body. Unbroken cholesterol and triglycerides leave the body through feces, which promotes weight loss.

Orsoten is prescribed for:

obesity with a BMI above 30 kg;
obesity with a BMI over 28 kg and associated risk factors in combination with an anti-calorie diet.

Effect of the drug

Do not use Orsoten for:

allergies to medicinal composition;
malabsorption;
cholestasis.

The medication is not used in pediatric practice or in the treatment of women during breastfeeding and pregnancy.

Capsules should be taken orally and washed down with a small amount of water. It is necessary to drink capsules before each meal or no later than 60 minutes after eating. Single dosage – 1 capsule (120 mg). When using more than 3 Orsoten capsules per day, its therapeutic effect is not enhanced and the weight loss process is not accelerated.

You do not need to take the medicine while eating a meal that does not contain fat. The medication course cannot last longer than 2 years. Patients with impaired renal and liver function, as well as elderly patients, do not require dose adjustment.

Side symptoms:

disruption of the gastrointestinal tract;
flatulence and frequent urge to defecate;
steatorrhea;
oily discharge from the anus;
frequent bowel movements and diarrhea;
fecal incontinence;
tooth decay and gum soreness;
hypoglycemia in diabetes;
headache and flu symptoms;
infection of the urethral organs;
bronchospasms and Quincke's edema;
dermatological rashes and urticaria;
hepatitis and increased transaminases;
gallstones.

Liponorm

Liponorm is a herbal medicine that is used for weight loss and lowering the cholesterol index. The herbal medicine contains the following ingredients: chitosan, garcinia, grapefruit and orange, fennel, anise and eleuthero, ginger and blueberries, red pepper.

Liponorm also contains B vitamins - B1, B2, B6, B12, folic acid and vitamin C, and also contains a whole complex of micro and macroelements and minerals.

Nicotinamide in Liponorm reduces not only excess cholesterol, but also glucose, and is also a natural antioxidant. Grapefruit, blueberries and ginger also reduce cholesterol in the blood. Blueberries also restore the menstrual cycle in women.

Fennel activates the biliary system, which helps inhibit the synthesis of endogenous cholesterol. Ginger enhances the production of bile, through which the process of destroying lipids occurs and leaving them outside the body with feces.

The medication is used for:

weight loss through diet (as part of a weight loss complex);
hypercholesterolemia;
dyslipidemia.

The herbal medicine is not prescribed for:

hypersensitivity of the body to components;
kidney/liver dysfunction;
hypertension;
arrhythmias, ischemic heart disease and myocardial infarction;
angina pectoris and decompensated stage of myocardial failure;
vegetative-vascular dystonia;
type 1 diabetes;
ARVI, acute respiratory infections and infectious pathologies;
hyperthyroidism;
epileptic seizures;
ulcerative destruction in the gastrointestinal tract;
disturbances in hemostasis - erythrocytosis, anemia, thrombocytopenia;
systemic thrombosis and thromboembolism, as well as thrombophlebitis;
psoriasis;
oncological neoplasms.

Not prescribed in pediatric practice, during lactation and pregnancy.

Liponorm is taken orally. The tablets should be taken 30 minutes before meals. Dosage regimen: 1-2 tablets twice a day.

The maximum permissible daily dosage is 4 tablets. The duration of the medication course is 45-50 days. If absolutely necessary, the doctor will extend therapy to 90 days.

Side effects:

skin allergies and bronchospasms;
hyperglycemia;
the appearance of sugar in urine;
headache and dizziness;
overexcitation of the central nervous system and anxiety;
dyspepsia with flatulence and belching;
hypertension, tachycardia;
thrombocytosis;
dyspnea.

Tsefamadar

Cefamadar is a homeopathic medicine that is used in the treatment of excess weight. The homeopathic remedy is produced in tablets with the active ingredient - madara trituration. The drug is safe, has no toxicity to the body and does not cause side effects, and can be prescribed in pediatrics from 3 years of age.

The main principle of the medicine is to reduce the feeling of hunger, due to the effect of the medicine on the hunger centers in the brain. Cefamadar reduces appetite, which leads to a decrease in fat in alimentary-type obesity. The drug is prescribed to patients with increased weight over 27-30 kg.

The medicine is not prescribed to those patients who are allergic to the composition of the medicine, as well as to children under 3 years of age, women during pregnancy and lactation.

The dosage of the drug depends on the age of the patient:

3-6 years – 1 tablet once a day;
6-12 – 1 tablet twice a day;
after 12 years and adults – 1-3 doses per day, 1 tablet.

Before swallowing the tablet, chew it and drink it with a small amount of water. You need to take the medicine 10-15 minutes before meals. When treating with Cefamadar, you must follow a low-calorie diet. If a medication dose was missed, then the next dose should be taken as usual and not take a double dose. The medication is not addictive. The duration of the therapeutic course is determined by the attending physician, in accordance with the stage of obesity, the presence of concomitant pathologies and positive dynamics in the course of therapy.

Side effects of the drug are not pronounced, only at the beginning of therapy the following negative symptoms may appear:

increased appetite;
allergic reactions on the skin - hyperemia, rash and itching.

Styfimol

Stifimol is a combined herbal medicine, which is prepared in capsules with a herbal component - Garcinia Cambogia extract, and many other components are also present. Garcinia has been used for weight control in Southeast and South Asia for many centuries.

The main ingredient in garcinia is hydrox citric acid, which is a natural inhibitor of lipogenesis and also blocks the synthesis of cholesterol molecules in liver cells.

With the help of Stifimol, glycogen synthesis increases, which reduces appetite, and also activates the process of thermogenesis inside the body.

Chromium picolinate in garcinia corrects lipid and carbohydrate metabolism, and also maintains glucose levels within normal limits.

Stifimol is used for:

overweight;
tendency to gain excess weight.

Do not use the herbal medicine if the body is hypersensitive to the ingredients, as well as in pediatrics, pregnancy and lactation.

Stifimol is prescribed in 2-3 doses per day, 1 capsule. The medicine should be taken 10-15 minutes before meals or during meals. The course of therapy is 30-45 days. 2-3 months after the end of therapy, a second course of medication can be administered.

Negative symptoms:

disruption of the thyroid gland;
blood pressure fluctuations and hypertension;
tachycardia and arrhythmia;
disturbances in the gastrointestinal tract - dyspepsia, flatulence and diarrhea;
skin rashes.